Japanese knotweed is an excellent source of resveratrol, the chemical compound found in grapes–except Japanese knotweed contains high concentrations of trans-resveratrol, the active form of the compound most useful to the body. Japanese knotweed is quickly becoming the preferred source of resveratrol.
Benefits of Japanese Knotweed*
- Slows the ageing process
- Promotes a healthy microbiome
- Maintains healthy cardiovascular function
- Promotes healthy liver function
- Supports a healthy immune system
- Improves mood, sleep quality and boosts energy levels.
Trans-resveratrol is the chemical form of resveratrol best absorbed and utilised by the body. While red grapes are high in resveratrol, it must be converted into trans-resveratrol in the body. Japanese knotweed contains mostly trans-resveratrol (53%), making it the preferred source.
Trans-resveratrol inhibits each phase of tumor growth, by interacting with several cellular targets, thereby activating cell cycle arrest and death. At molecular level, it has been suggested that high concentration of polyphenols can induce the production of ROS, rather than reinforcing the antioxidant defense, and it has been hypothesised that this pro-oxidant function can play a pivotal role in resveratrol-induced apoptosis in tumor cells
trans-Resveratrol induces apoptosis via the mitochondrial pathway. trans-resveratrol was able to rapidly activate JNK and p38MAPK, although with different kinetics and to different extent.
Resveratrol Restores BRCA Oncosuppressors
Resveratrol inhibited the binding of labelled oestradiol to the oestrogen receptor and activated transcription of oestrogen-responsive reporter genes transfected into human breast cancer cells. Resveratrol can increase expression of the BRCA1 and BRCA2 oncosuppressors, involved in the aggressiveness of human breast cancer cell lines (TNBC). [R]
Antioxidant & Cardiovascular Support. Healthy Aging – Trans-Resveratrol: 450mg. Daily wellness, longevity and vitality come naturally when your body is in a state of harmony.
Werone Resveratrol 1 capsules provides 2250mg trans- Resveratrol per daily dose. These are 100% vegetarian, dairy free, no gluten-containing ingredients – Easily digestible plant-derived capsule, Laboratory tested for purity – Free of heavy-metal toxicity.
Adults take 1 – 2 capsules once per day.
Gelatin capsule, no fillers..
Not to be used during pregnancy or lactation. If you have a medical condition or take medications please consult with your doctor before using this product. Keep away from children. Use only as directed on label. Safety sealed for your protection. Keep bottle capped at all times and store in a cool dry place. Natural separation may occur. This does not affect product quality.
trans-Resveratrol induces apoptosis in human breast cancer cells by the activation of MAP kinases pathways
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Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.
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