ReMEM™ – Cognitive Function Support for Alzheimers / Dementia

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ReMEM™ contains a compound called ‘Huperzine A’. This is extracted from a Chinese plant commonly known as northern firmoss (Huperzia serrata), Huperzine A is a naturally derived acetylcholinesterase enzyme inhibitor AChE and has been the subject of many clinical studies on it’s usefullness with Cognitive generation and it’s effects on preserving Acetylcholine in the brain, which is essential for memory recall. * Under Paypal Restrictions, this item may not be shipped to Ireland *

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Description

A Road-block Against Early Dementia,  Alzheimers, & more!

Dementia is a group of symptoms caused by gradual death of brain cells. The loss of cognitive abilities that occurs with dementia leads to impairments in memory, reasoning, planning, and behaviour.

While the overwhelming number of people with dementia are elderly, dementia is not an inevitable part of aging; instead, dementia seems to be caused by a combination of heavy metal and chemical toxicity combined with poor nutrition according to a recent study.

Dementia or Alzheimers as it is known in it’s more severe state is avoidable with the correct strategy according to recent research from Dale Bredesen who developed a protocol called MEND™ and was able to reverse cognitive decline in 8 out of 10 patients over an 8 to 24 month period using a nutritional approach.

11 Possible Reversible Causes of Dementia

1. Mercury and other heavy metal toxicity from Vaccinations, Dental Amalgams, TunaFish etc
2. Toxins in food, water, air, work/home environments
3. Dirty APOE4/4 (fat breakdown gene), MAOA and/or NOS3 Genes (see Dirty Gene Finder™)
4. Effects of prescription medications such as Statins.
5. Nutritional imbalances and deficiencies, some caused by Vegetable oils
6. Hormonal imbalances (T3 thyroid, HGH, estrogen, testosterone and others)
7. Inflammation from low-level infections, mold, food allergies, or Lyme Disease
8. Inadequate physical activity, mental stimulation and social interaction
9. Stress, especially from life changes and how we process information
10. Sleep and breathing problems related to oxygen deficiency
11. Traumatic Brain Injury

Cardiovascular disease may contribute to clogged cerebral arteries, cutting down blood flow to the brain and contributing to the development of Alzheimer’s disease. Dietary components that may increase the risk of cognitive dysfunction include pork consumption, hormones in dairy, blue-green algae supplements, spirulina, copper, glycotoxins, the neurotoxin known as BMAA (found mostly in seafood), aluminum, and excess iron.

Those who eat meat such as chicken, pork, and beef, as well as seafood, may have triple the risk of being diagnosed with dementia, compared to long-time vegetarians. This may be in part because high fat, high protein foods exposed to high heat can form glycotoxins, the consumption of which may predict cognitive decline over time.

The above list reveals some of the aspects which a successful strategy might include.  It is no surprise that heavy metals play a prominent role in our current epidemics of ‘mystery illnesses’ and degenerative diseases such as Alzheimer’s and dementia. Despite all of this, heavy metal toxicity remains a relatively unexplored (and untreated) phenomenon—for everything we know about the dangers of heavy metals, there is a great deal more that has yet to be discovered. Heavy metals just may be the premier ‘hidden antagoniser’ and mystery illness trigger in so many of us.

Poor APOE4 Gene Function – rs7412/rs429358 (brain inflammation)
The human APOE gene exists as three polymorphic alleles—ε2, ε3 and ε4—which have a worldwide frequency of 8.4%, 77.9% and 13.7%, respectively.However, the frequency of the ε4 allele is dramatically increased to ~40% in patients with AD.ApoE regulates lipid homeostasis by mediating lipid transport from one tissue or cell type to another. In peripheral tissues, ApoE is primarily produced by the liver and macrophages, and mediates cholesterol metabolism in an isoform-dependent manner. ApoE4 is associated with hyperlipidaemia and hypercholesterolemia, which lead to atherosclerosis, coronary heart disease and stroke.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726719/

Where ReMEM™ comes in is providing some early mental clarity for the person to be able to make some important decisions in agreeing to the nutritional strategy as some habits will need changing and new supplements and foods introduced. Fortunately, as shown in this short film below, positive results can be achieved in a matter of days and weeks but it needs to start with Heavy Metal Detox (see below). Fortunately there are powders to make a metal chelation drink.

 

This Short Video Explains Some of The Problem Occurring with Dementia & Alzheimer Patients

 

ReMEM™ contains a compound called ‘Huperzine A’. This is extracted from a Chinese plant commonly known as northern firmoss (Huperzia serrata), Huperzine A is a naturally derived acetylcholinesterase enzyme inhibitor AChE and has been the subject of many clinical studies on it’s usefullness with Cognitive generation and it’s effects on preserving Acetylcholine in the brain, which is essential for memory recall.

Acetylcholine(ACh) is a crucially important neurotransmitter that is involved with memory formation/recall, concentration and rate of learning. Acetylcholine (ACh), a neurotransmitter which is essential for processing memory and learning, is decreased in both concentration and function in patients with  Dementia and Alzheimer’s disease.

Cholinesterase inhibitors (also called acetylcholinesterase inhibitors) abbreviated AChEI’s are a group of medicines that can block the normal breakdown of acetylcholine by opposing the enzyme AChE which breaks down Acetylcholine (ACh). This increases levels of acetylcholine in the synaptic cleft (the space between two nerve endings).

Acetylcholine is the main neurotransmitter found in the body and has functions in both the peripheral nervous system and the central nervous system. For example, acetylcholine is released by motor neurons to activate muscles; acetylcholine also has an important role in arousal, attention, learning, memory and motivation.

Acetylcholinesterase inhibitors (AChE’s) are employed to reduce the rate at which acetylcholine (ACh) is broken down, thereby increasing the concentration of ACh in the brain and combating the loss of ACh caused by the death of cholinergic neurons. There is evidence for the efficacy of these medications in early onset of Dementia and some evidence for their use in advanced stages.

Interestingly, the neuroprotective effect of Huperzine A is not correlated with its AChE inhibition, suggesting that the therapeutic effect of HupA may be exerted via a multitarget mechanism. In addition to acetylcholinesterase inhibition, Huperzine A within ReMEM™ can also be seen as neuroprotective against glutamate,[R] beta-amyloid pigmentation,[R] and H2O2-induced toxicity.[R]

The drug versions of Cholinesterase inhibitors tend to cause strong side effects such as vasodilation, constriction of the pupils in the eyes, increased secretion of sweat, saliva and tears, slow heart rate, mucus secretion in the respiratory tract and constriction of the airways, however, the herbal sourced,  Cholinesterase inhibitors such as Huperzine A in ReMEM is preferable for usage as a cholinergic since it has been reported to have less cholinergic-related side-effects,[15] possibly through its high affinity for brain G4 acetylcholine resulting in less availability for systemic butrylcholine inhibition, which leads to various systemic effects which may be seen as side effects.[16][17]

 

 

Suggested Usage
Take 1 to 3 capsules very early morning with A2 milk and then 1-2 capsules 6 to 8 hours later, However start slowly with half capsule to gradually introduce it as some people can be sensitive to AChE inhibitors. Take 1 week off every 5 weeks. ReMEM Protocol includes Vitamin D3, Omega 3(Fish Oil), Vit B, Lemon Balm Tea, Coconut oil, reduce Gluten, Sugars & Red Meats (heme Iron). If you know you have the APOE4/4 Variant gene, then it is even more important to cut out sugars and simple carbohydrates(gluten) from your diet and focus upon a healthy ketogenic diet, avoidance of head injuries and improve sleep regime.  Include other Antioxidants such as PQQ, NAC, ALA, & Liposomal Glutathione.

ReMEM doesn’t need to be taken with food due to it’s water solubility.  It takes just 15 minutes to enter the blood stream and can result in a spike of clarity for the first two hours and then drops to a very usable level for the next 6 to 8 hours.

It could take a few hours to a few weeks to see significant improvements of taking ReMEM™, but by also working on the dietary and lifestyle changes which are detailed in BiohackIT can improve results further. Additional supplements which are suggested to work alongside ReMEM™ and available from our shop:

B12 methylcobalamin, Vitamin D3, Omega-DHA oilCoenzyme Q10,  Nutritional Yeast,  Curcumin, R-ALA, Green Tea and to reduce/eliminate Gluten, Processed foods, Animal Proteins and Vaccinations. Additional dietary details are to be found in BiohackIT tool.

 

 

Quality Assurance Declaration

Lab-Tested
Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.

 

Nutraceutical Disclaimer

These statements have not been evaluated by the Food and Drug Administration or MHRA and the items are not intended to diagnose, treat, cure, or prevent any disease nor are they associated, endorsed, affiliated or sponsored by Anthony William, Medical Medium® Joe Tippens or Jim Gordon.

 

Metal Chelation Protocol
In the modern world, the accumulation of heavy metals and other toxins, along with inherited mercury deposits, is inevitable—that’s the bad news. The good news is that it is relatively easy to get rid of the heavy metals that you may have already accumulated (both generational and recent), and there are steps you can take to minimise your future exposure, read this article.

Keep out of reach of children. Keep your health care practitioner informed when using this product. Do not use if you are pregnant or nursing. Huperzine A should be used with caution by individuals with known heart rhythm disorders or chronic asthma. Anyone undergoing major surgery should alter the anesthesiologist to Huperzine A supplementation. May potentiate pharmaceutical MAO-inhibitors.

Testimonials

Seems to be helping my husband with dementia.. …
By T. Ahlberg
Seams to be helping my husband with dementia… Don’t notice much until l we run out…. and then I’m running to buy more!! Definite difference!

For anyone Experiencing Memory Loss This Pill Does Wonders
By Amanda
I have a relative that has dementia and cannot sing higher praises for them. Recall after 3 months is pretty good and her memory definitely has improved, I bought these because of a study I found where they used acupuncture and Huperzine A on people with dementia for 3 months, they found their memory improved around 70%.

Reversed permanent side effects from antipsychotics
By shopshop
My doctor misdiagnosed me and put me on antipsychotics for bipolar disorder. Worst pills I’ve ever taken, even after I discontinued the side effects would not go away. I was sleeping 12 hours a day, lethargic. Worked up the ability to do a little research, and cane across this supplement. Given to people with dementia, Alzheimer’s, and general memory problems, huperzine a has shown to increase acetylcholine in countless studies. I kid you not, from the FIRST tablet I started feeling better, I was more awake, my mental functions started coming back to me. After 4 days of use. I didn’t need these to stay awake anymore, whatever damage the antipsychotics did to my brain, this supplement practically reversed it. I thank god i found this supplement.

Five Stars
By AC
These are like a sharpness pill its noticeable can’t explain how good they are

Works well, but start small.
By Emmanuel Colin August
Definitely works, but try smaller doses first. I take this occasionally for focus purposes, but it’s given me a migrane and dizziness once or twice. If possible, I suggest getting the 100mcg pills and cutting them in half and if that doesn’t work for you, slowly up the dosage until it does.

I have definitely felt a change in my ability to focus 95% of the time (tho sometimes it kicks in too late) and I definitely have had a better short-term memory during these occasional dosages.

Returned to almost normal for me!
By Brenda J. Peterson
First let me say my memory was never great for recall even as a kid.I just did better on multiple choice question as opposed to fill in the blank. As I 47 years old and have trouble sometimes quickly thinking of the peoples names in my office here at work,that can get embarrassing.It happened a lot. The last few years have been really bad.

When I first started taking the pills( I am only taking 1 a day) my memory recall seemed worse than before this went on for 2-3 weeks. I still continued on with them hoping they would work. Finally,I could recall things quickly and words are coming to me quite readily now. I am thinking of upping it to two times a day but not sure because I feel like my memory is now back to pretty typical for me. I did have on Friday where I couldn’t think of one of my coworkers names but I think I was off my normal routine. These instances(memory lapses) are few and far between now. I will report back if I see any more improvement I am ordering more now. I will also report back if I up the dose to 2.

Terrific!
By Anon
This helps me with cognition, memory and verbal fluency. It requires very careful dosing. I don’t use it more than one tablet three times a week. More than that and I get cholinergic symptoms (anything from hypersalivation to anxiety).

Excellent for focus and learning.
By Kelaine fes
Should be cycled off every 2 weeks of use as you will build up a tolerance..
Did not have unpleasant side effects, although I did remember dreams much better in the first days of use.

Five Stars
By Snena Reek
It helps a lot for my mother’s cognitive decline, she has 100% more memory 🙂

Great for Brain Fog
By Bambi
This stuff is amazing. I noticed a marked difference in clarity of thinking within a few days. I take it 2-3 times a day.

Works! Monitor your dosage.
By Denise Vincent
Huperzine A is an effective acetylcholine agonist. However, be very careful with the dosage, else you may experience a hot flash. I’ve found it effective for boosting time awareness following chemotherapy.

Great alternative to mestinon for MG patients

By chandar e hall
I have myasthenia gravis and this is a great alternative to mestinon, I actually feel that it works better than mestinon (I have pretty severe MG so it does work for people who needed higher dose and extended release mestinon). I don’t have all the horrible side effects that mestinon gave me.

Clinical Studies:

  1. Howes MJ, Perry NS, Houghton PJ.Plants with traditional uses and activities, relevant to the management of Alzheimer’s disease and other cognitive disorders.Phytother Res. (2003)
  2. Ha GT, Wong RK, Zhang Y. Huperzine a as potential treatment of Alzheimer’s disease: an assessment on chemistry, pharmacology, and clinical studies. Chem Biodivers. (2011)
  3. Ma X, Gang DR. In vitro production of huperzine A, a promising drug candidate for Alzheimer’s disease. Phytochemistry. (2008)
  4. Total Synthesis of (−)-Huperzine A.
  5. Wang XD, et al. Comparison of the effects of cholinesterase inhibitors on {3H}MK-801 binding in rat cerebral cortex. Neurosci Lett. (1999)
  6. Rajendran V, et al. Synthesis of more potent analogues of the acetylcholinesterase inhibitor, huperzine B. Bioorg Med Chem Lett. (2002)
  7. He XC, et al. Study on dual-site inhibitors of acetylcholinesterase: Highly potent derivatives of bis- and bifunctional huperzine B. Bioorg Med Chem. (2007)
  8. Qian BC, et al. Pharmacokinetics of tablet huperzine A in six volunteers. Zhongguo Yao Li Xue Bao. (1995)
  9. Li YX, et al. Pharmacokinetics of huperzine A following oral administration to human volunteers. Eur J Drug Metab Pharmacokinet. (2007)
  10. Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine.
  11. Chemistry, Pharmacology, and Clinical Efficacy of the Chinese Nootropic Agent Huperzine A.
  12. Development of huperzine A and B for treatment of Alzheimer’s disease.
  13. Boudinot E, et al. Effects of acetylcholinesterase and butyrylcholinesterase inhibition on breathing in mice adapted or not to reduced acetylcholinesterase.Pharmacol Biochem Behav. (2005)
  14. Lane RM, Potkin SG, Enz A. Targeting acetylcholinesterase and butyrylcholinesterase in dementia. Int J Neuropsychopharmacol. (2006)
  15. Ved HS, et al. Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate. Neuroreport. (1997)
  16. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
  17. Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine.
  18. The NMDA receptor ion channel: a site for binding of Huperzine A.
  19. Ma T, et al. Huperzine A promotes hippocampal neurogenesis in vitro and in vivo. Brain Res. (2013)
(Common misspellings for Huperzine-A include Huperzine, huperizine, hoop

 

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