Lauric acid is a 12-carbon medium-chain fatty acid (MCFA) found naturally in human breast milk (6.2% of total fat) and coconut oil (47.5% by weight). Lauric acid was originally discovered when microbiologists studied human breast milk to determine the protective (antiviral and antibacterial) substances which protected infants from microbial infections. Other fatty acids were also found to have antimicrobial actions but lauric acid was found to be the most active. Lauric acid is able to disrupt the cell membrane of gram positive bacteria by physicochemical (physical and chemical) processes. Once inside the cell, it can interfere with bacterial cell signal transduction and gene transcription processes. Its activity is generally better at low pH and is diminished by Mg2+ and Ca2+
A chemical reaction, known as esterification¹, combines lauric acid and glycerol to yield an amazing compound known as monolaurin (glycerol monolaurate). This reaction can occur within our body and in a laboratory. Monolaurin acts as a surfactant², which possesses an even greater antiviral and antibacterial activity than its precursor, lauric acid. Monolaurin, when given orally, at therapeutic doses between 2,500 – 9,000 mg/day is generally well tolerated, with loose bowels as the only negative concern. Monolaurin has been extensively studied at medical research centers, including the Center for Disease Control (CDC), because of its high antimicrobial (antiviral, antibacterial, antifungal, antiyeast, and antiprotozoal) activity. These studies have provided information about the antiviral and antibacterial mechanisms of monolaurin. Monolaurin was found to be effective against certain Lipid Coated Bacteria (LCBs) and Lipid Coated Viruses (LCVs) – enveloped DNA and RNA viruses.
¹Esterification: Esterification is the generic term for the chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials and often have a characteristic pleasant, fruity odor. This leads to their extensive use in the fragrance and flavor industry
²Surfactant: Surfactants are compounds that lower the surface tension of a liquid, allowing easier spreading, and lowering of the interfacial tension between two liquids, or between a liquid and a solid. Surfactants may act as detergents, wetting agents, emulsifiers, foaming agents, and dispersants.
SIBO, HIV-1, Influenza virus, paramyxoviruses, rubeola virus, bronchitis virus, and the herpes family of viruses (Epstein-Barr (EBV), Cytomegalovirus (CMV), zoster (Chicken pox), varicella-zoster (shingles) and herpes type I and II). Sadly, monolaurin had no effect on diseases caused by non-enveloped viruses such as the polio virus, coxsackie virus, encephalomyocarditis virus, rhinovirus, and rotaviruses.
The antiviral and antibacterial action attributed to monolaurin are that of making soluble the fats in the protective envelope, causing the disintegration of the microbial membrane. This process works more efficiently when combined with metal chelating agents, such as EDTA and Bovine Colostrum ( lactoferrin), and mucolytics, like NAC. See Pathogest which includes Monolaurin.
Die-off of pathogenic bacteria should follow usage of antibacterials, take Activated Charcoal to soak up the debris and black tart morello cherries to reduce the levels of ammonia.
Recent publications have shown that monolaurin and lauric acid inhibit the replication of viruses by interrupting the communication and binding of the virus to host cells and thus preventing the uncoating of viruses necessary for replication and infection. Other studies have shown that monolaurin is able to remove all measurable infectivity by directly disintegrating the protective bacterial and viral lipid envelope. Binding of monolaurin to the viral envelope also makes the virus more susceptible to degradation by host defenses, heat, or ultraviolet light. (Projan et al 1994, Hornung et al 1994, Witcher et al, 1993)
Suggested Usage: Take 2-3 Monolaurin capsules a day with food. Up to 3g a day for more challenging issues.
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