LiverLung (NAC) is our version of the amino acid N-acetyl Cysteine which is a strong Glutathione Precursor and detoxing agent. It helps neutralize the byproducts of ingested fats and alcohol metabolism and protect the body from the damaging effects of chemotherapy, cigarette smoke, heavy metals, and various other substances.
NAC has been used since the 1960’s to help treat respiratory conditions by helping thin mucus and increase immunity and may be especially useful for people with chronic bronchitis, which is often associated with smoking. Preliminary studies indicate that NAC may also help increase levels of a type of immune cell called CD4+ in both healthy people and people with HIV.
The antioxidant properties of NAC have been shown to help muscle tissue recover more quickly after exercise. NAC has been used successfully to detoxify the body, especially the liver in cases of acetaminophen poisoning. It also helps people suffering from alcohol poisoning and those who are simply feeling hungover after a night of drinking.[youtube src=”http://www.youtube.com/embed/tvel1kOuUO4″]
NAC is coveted for its anti-aging properties, most likely connected to its role in the substantial release of glutathione in the body, which fights the cellular damage of oxidative stress, a key to fighting against aging. Its ability to inhibit viral replication may be useful in fighting viral infections from HIV to the flu. NAC can also help with the formation of skin and hair.
NAC helps neutralize the byproducts of ingested fats and alcohol metabolism and protect the body from the damaging effects of chemotherapy, cigarette smoke, heavy metals, and various other substances.
The strong and growing links between oxidative stress, inflammation, and cancer make NAC a natural go-to compound for cancer chemoprevention. True to form, NAC has multiple anti-cancer activities acting at multiple targets to provide layers of cancer protection against a large variety of cancer types. NAC induces programmed cell death (apoptosis) in multiple types of human cancer cells.62 In human gastric cancer cells, NAC not only induces apoptosis, but also stops DNA synthesis, preventing cancer the cells from replicating. In melanoma cells, NAC inhibits NF-kB, preventing expression of signaling molecules needed by the cancer for growth.
NAC inactivates and promotes destruction of c-Src, a chemical control molecule that is overproduced in many human cancers, providing a completely unique means of slowing or stopping tumor development.65 Finally, NAC protects DNA from breakage induced by ionizing radiation, but does not prevent cell destruction by radiation. That’s a vital finding because it means that NAC might allow radiation therapy to effectively kill cancer cells while minimizing the risk of so-called secondary cancers that could otherwise arise as side effects of the radiation.
Animal studies strengthen the case for NAC still further. NAC protects mice from cigarette smoke-induced lung cancers and other lung changes, a finding with enormous implications not only for current smokers but for ex-smokers and people exposed to second-hand smoke. NAC protects rats from chemically-induced liver cancers immediately following tumor initiation. This early interference with cancer development bodes well for NAC as a chemopreventive agent in the many human toxin-related cancers.
Human studies are similarly encouraging, even in the most challenging patient groups such as smokers. A randomized, double-blind chemoprevention trial of NAC 600 mg twice daily for 6 months vs. placebo in otherwise healthy smokers showed a significant reduction in formation of damaged or oxidized DNA segments, telltale early markers of cancer development in lung fluid. The same study also demonstrated reductions in abnormal, pre-cancerous cell changes in the mouths of supplemented smokers. These effects support the scientists’ conclusion that NAC can reduce tobacco smoke carcinogenicity in humans.
Colon cancer is another malignancy with strong links to oxidative stress and inflammation. Preliminary studies in humans show a 40% reduction in colorectal polyps in patients given 600 mg per day of NAC, compared with controls. In a group of people with a previous history of pre-cancerous colonic polyps, 800 mg per day of NAC for 12 weeks significantly reduced the proliferative index, indicating a decreased risk of colon cancer.
Supplementing with 600 – 1200 mg per day of NAC appears to be an entirely appropriate means of adding to your general cancer-prevention strategy.
Gastritis, Ulcers, Cancer, and Helicobacter pylori
Helicobacter pylori is a bacterium that colonizes various regions of the stomach and upper part of the small intestine. H. pylori infection produces major oxidative stress on tissues already vulnerable to extremes of pH and other chemical challenges, and the resulting inflammation produces pain and promotes development of gastric and esophageal cancers. NAC is an obvious candidate for fighting H. pylori infections, both because of its powerful ability to interfere with the oxidant-inflammation connection, and also because of its potential to break down some of the gastric mucous layer beneath which the organism hides.
NAC fights H. pylori in at least two ways. It markedly inhibits growth of H. pylori both in culture dishes and in live mice, helping to reduce the total load of organisms present. But NAC also powerfully regulates gene expression in stomach lining cells, reducing hydrogen peroxide production induced by H. pylori, and decreasing activation of NF-kB and subsequent release of inflammatory cytokines.
In human trials NAC improves eradication rates of H. pylori produced by standard treatment with antacids and antibiotics, when given at doses of 1,200 mg per day. However, NAC alone won’t eradicate H.Pylori, you will need to adjust your diet to remove grains, pasteurised milk and some fruits / vegetables, include some botanicals such as mastic, turmeric, cloves and wormwood, soothe and heal the gut with DGL, aloe vera and bone broths, here is our H.Pylori protocol along with the products.
People who have gastritis or gastroesophageal reflux disease (GERD) may be infected with H. pylori and may benefit from supplementation with 1200 mg per day of NAC, especially during co-treatment with drugs to eradicate the organism.
N-acetyl cysteine is a broad-spectrum compound traditionally under-utilized in conventional medicine. A burst of new clinical research reveals that NAC exerts dual effects, functioning both as a powerful antioxidant that replenishes cellular antioxidant systems (glutathione in particular) and also as a potent modulator of gene expression, regulating inflammation at multiple, fundamental levels. It has been shown to be an effective intervention against influenza, chronic lung diseases, cancers, insulin resistance, and gastritis caused by H. pylori. NAC’s further value is shown in its ability to mitigate otherwise inevitable metabolic and immunological disturbances caused by exercise.
Suggested Use: Suggestions: Take 1 to 3 capsules daily. Optimal levels are dependent on many variables. For best antiviral and FLU protection take 2 x day and drink Green Tea.
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Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.
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