Note: This item has been superceded by CURCUBOS (Water-soluble Curcumin).
C3 Complex refers to the three main compounds; Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin collectively known as Curcuminoids provided by Sabinsa.
Patented for its unique composition ratio and use, research shows C3 Complex offers consumers a wide range of health benefits. Due to its broad positive impact on many physiological activities in the body, C3 Complex is the first of its kind in a category of nutrients we described in 1995 as Bioprotectant. Perhaps better understood as a Super Anti-oxidant C3 Complex provides optimal protection and integrity to biological systems.
A significant amount of research, both pre-clinical and clinical, exists on curcumin extract compositions; but the majority of the materials used in these studies and reported in published literature are not commercially available to consumers. This is where C3 Complex is different.
Curcumin C3 Complex is a safe, efficacious and clinically tested material that is certified by NSF International for potency and specification compliance. If you are not sure of the curcumin extract source in your supplement, ask your retailer or manufacturer of the product to specify Curcumin C3 Complex on the label. Consumers can trust the consistency and quality of this patented composition in their dietary supplement formulations.
Most degenerative diseases are driven by chronic, sub-clinical inflammation. The old view of the inflammation is that it represents the healing process. This is true to a certain extent; however when the inflammation becomes chronic, it becomes a disease.
Today the study of inflammation has gone from the tissue levels deeper into the nuclear level. Cell-signaling molecules have been identified which stimulate the gene that induce the expression of the COX enzyme, which in turn induce inflammation.
Nuclear Factor-ĸB: The Master Regulator of Inflammation
Nuclear Factor-Kappa B (NF-ĸB), as the ‘master switch’, is the primary means by which inflammation is ‘adjusted’.
- In the normal state NF-ĸB resides in the cytoplasm of the cell and is bound to its inhibitor—IkB (Inhibitor of ĸB)
- Injuries and inflammatory stimuli, such as free radicalstrigger the release NF- ĸB from IkB
- The free NF-ĸB, now moves into the nucleus andactivates the genes responsible for expressing cyclooxygenase-2 (COX-2)
- This leads to inflammation
NF-ĸB activation is a major mediator of inflammation in most diseases and inhibition of NF-ĸB can help prevent/delay the onset of the disease. Curcuminoids―natural compounds derived from turmeric roots, inhibit NF-ĸB.
“A daily dose of 3.6 g curcumin achieves pharmacologically efficacious levels in the colorectum with negligible distribution of curcumin outside the gut. Consumption of 3.6g of Curcumin daily is linked with inhibition of PGE2” http://www.ncbi.nlm.nih.gov/pubmed/15668484
Quality Assurance Declaration
Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.
Nutraceutical DisclaimerThese statements have not been evaluated by the Food and Drug Administration or MHRA and the items are not intended to diagnose, treat, cure, or prevent any disease nor are they associated, endorsed, affiliated or sponsored by Anthony William or Medical Medium® or Joe Tippens.