Apple Pectin – 700mg Capsules

£ 13.50£ 18.50

Clear
Use 1350 - 1850 points to purchase this product!

Description

Apple pectin may be just one more reason why the phrase “an apple a day keeps the doctor away” has endured. What exactly is pectin? It’s a complex carbohydrate, a soluble fibre found in the walls of plant cells.  The actual amount of pectin found in the cells varies by each plant. Overall, pectin content is typically higher in legumes and certain fruits. For instance, apple, grapefruit, orange and apricot are known to have high levels of pectin. There are many health benefits associated with pectin including:

  • regulating the digestive system
  • lowering blood pressure
  • lowering glucose levels
  • lowering  bad cholesterol levels

While pectin alone certainly has a number of health benefits, apple pectin in particular has some other medicinal advantages. Its primary use is as a natural remedy for digestive disorders. Since apple pectin is high in fiber, it is used to help regulate bowel movements and once it arrives in the colon it starts creates butyrate (HDAC Inhibitor) via fermentation with the colonic flora which has been shown to  induce apoptosis in colonocytes in vitro in a p53-independent manner .

It can help firm stools and reduce inflammation associated with diarrhoea, as well as help with constipation. It is also used to help treat colitis, irritable bowel disease, and other related digestive disorders, apple pectin has also been found to have the following properties.

  • HDAC Inhibitor
  • Protects Cells
  • Prevents Carcinogenesis
  • Lowers Colonic Inflammation
  • Activates Natural Killer T and B Cells

In 1825, a French chemist and pharmacist, Henri Braconnot, who was an expert in the extraction of active components from plants, was the first to discover a heteropolysaccharide with gelling properties which he named “pectic acid” (in ancient Greek πηκτ ικóς meaning coagulant).

Pectin is a family of complex polysaccharides, which are found in high amounts in plant primary wall. The main role of the plant wall components is to give mechanical strength to plants, to maintain an extracellular water phase by imbibition and to provide a barrier from external environment.

The exact chemical structure of pectin is still under debate. Pectins are a family of covalently linked galacturonic acid-rich polymers. Until now, three main pectic polysaccharides have been isolated from plant wall whose structure has been identified. They are homogalacturonan (HG), rhamnogalacturonan-I (RG-I) and substituted galacturonans (GS).

Suggested Usage:
Take 2 capsules with water 30 mins before a meal. Combine with Algae DHA for greater therapeutic effect [R]

 

Quality Assurance Declaration

Lab-Tested
Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.

 

Nutraceutical Disclaimer

These statements have not been evaluated by the Food and Drug Administration or MHRA and the items are not intended to diagnose, treat, cure, or prevent any disease nor are they associated, endorsed, affiliated or sponsored by Anthony William, Medical Medium® Joe Tippens or Jim Gordon.

 

Clinical Studies:
Anti-cancer activities of pH- or heat-modified pectin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792700/

 

  • Atmodjo M. A., Hao Z., Mohnen D. (2013). Evolving views of pectin biosynthesis. Annu. Rev. Plant Biol.64 747–779 10.1146/annurev-arplant-042811-105534 [PubMed] [Cross Ref]
  • Attari F., Sepehri H., Delphi L., Goliaei B. (2009). Apoptotic and necrotic effects of pectic acid on rat pituitary GH3/B6 tumor cells. Iran Biomed J. 13 229–236 [PubMed]
  • Avivi-Green C., Madar Z., Schwartz B. (2000a). Pectin-enriched diet affects distribution and expression of apoptosis-cascade proteins in colonic crypts of dimethylhydrazine-treated rats. Int. J Mol Med. 6 689–98[PubMed]
  • Avivi-Green C., Polak-Charcon S., Madar Z., Schwartz B. (2000b). Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition. Oncol. Res. 12 83–95 10.3727/096504001108747558 [PubMed] [Cross Ref]
  • Heitman D. W., Hardman W. E., Cameron I. L. (1992). Dietary supplementation with pectin and guar gum on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. Carcinogenesis 13 815–818 10.1093/carcin/13.5.815 [PubMed] [Cross Ref]
  • Hensel A., Meier K. (1999). Pectins and xyloglucans exhibit antimutagenic activities against nitroaromatic compounds. Planta Med. 65 395–399 10.1055/s-1999-14013 [PubMed] [Cross Ref]
  • Hsieh T. C., Wu J. M. (1995). Changes in cell growth, cyclin/kinase, endogenous phosphoproteins and nm23 gene expression in human prostatic JCA-1 cells treated with modified citrus pectin. Biochem. Mol. Biol. Int. 37 833–841 [PubMed]
  • Inohara H., Raz A. (1994). Effects of natural complex carbohydrate (citrus pectin) on murine melanoma cell properties related to galectin-3 functions. Glycoconj. J. 11 527–532 10.1007/BF00731303 [PubMed][Cross Ref]
  • Jackson C. L., Dreaden T. M., Theobald L. K., Tran N. M., Beal T. L., Eid M., et al. (2007). Pectin induces apoptosis in human prostate cancer cells: correlation of apoptotic function with pectin structure.Glycobiology 17 805–819 10.1093/glycob/cwm054 [PubMed] [Cross Ref]
  • Jiang J., Eliaz I., Sliva D. (2013). Synergistic and additive effects of modified citrus pectin with two polybotanical compounds, in the suppression of invasive behavior of human breast and prostate cancer cells. Integr. Cancer Ther. 12 145–152 10.1177/1534735412442369 [PubMed] [Cross Ref]
  • Johnson K. D., Glinskii O. V., Mossine V. V., Turk J. R., Mawhinney T. P., Anthony D. C., et al. (2007).Galectin-3 as a potential therapeutic target in tumors arising from malignant endothelia. Neoplasia 9 662–670 10.1593/neo.07433 [PMC free article] [PubMed] [Cross Ref]
  • Kang H. J., Jo C., Kwon J. H., Son J. H., An B. J., Byun M. W. (2006). Antioxidant and cancer cell proliferation inhibition effect of citrus pectin-oligosaccharide prepared by irradiation. J. Med. Food 9 313–320 10.1089/jmf.2006.9.313 [PubMed] [Cross Ref]
  • Kanthamneni N., Chaudhary A., Wang J., Prabhu S. (2010). Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer. Int. J. Oncol. 37 177–185[PMC free article] [PubMed]
  • Kolar S., Barhoumi R., Jones C. K., Wesley J., Lupton J. R., Fan Y. Y., et al. (2011). Interactive effects of fatty acid and butyrate-induced mitochondrial Ca(2)(+) loading and apoptosis in colonocytes. Cancer117 5294–5303 10.1002/cncr.26205 [PMC free article] [PubMed] [Cross Ref]
  • Kolar S. S., Barhoumi R., Callaway E. S., Fan Y. Y., Wang N., Lupton J. R., et al. (2007). Synergy between docosahexaenoic acid (DHA) and butyrate (Pectin-Induced) elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 293 G935–G943
    10.1152/ajpgi.00312.2007 [PMC free article] [PubMed] [Cross Ref]

 

Additional information

Weight N/A
Size

,

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.