AdrenalMagic™ can benefit everyone in stressful life situations. Contains synergistically balanced vitamins and minerals, herbs, and micro-nutrients. Supports the (hormonal) endocrine system which is the body’s ability to metabolise hormones.
There is a pervasive myth circulating in alternative health circles that the adrenal glands can become fatigued and become unable to supply the required hormones in time of stress, however, this is not been proven scientifically. Yes, stress induced, sub-optimal adrenal function is a real thing, but it’s not produced by tired adrenals. Instead, it’s a result of a hypothalamic pituitary adrenal (HPA) axis dysfunction. It’s more brain and nervous system than it is glandular.
Dysfunctional HPA axis function is fundamentally caused by Inflammation and oxidative stress (OS) and also commonly what people are calling ‘adrenal fatigue‘.
Adrenal fatigue is actually more of a miscommunication in the brain than it is an adrenal problem. This is why most mainstream medical doctors do not acknowledge that adrenal fatigue exists. But that doesn’t mean your symptoms are just in your head. Your doctor does not believe in adrenal fatigue because in medical literature there no evidence of its existence.
The hypothalamus ‘senses’ inflammation and oxidative stress. In their presence, the hypothalamus sends out ‘signals’ to the body to behave in a way that makes us feel tired, sick, unmotivated, etc… (via orexin, neurotransmitters, and other hormones).
Orexin , also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. The most common form of narcolepsy, in which the sufferer experiences brief losses of muscle tone (cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells that produce it. Orexin-A strongly promotes wakefulness, increases body temperature and locomotion, and elicits a strong increase in energy expenditure.
The active thyroid hormone (T3) is decreased by inflammation and oxidative stress, which independently causes problems of its own. The tiredness you feel is mainly because of your hypothalamus (suppression of orexin) and secondarily because of low T3 and low pregnenolone.
In short, the most common reason we are fatigued is because of inflammation (IL-1, TNF) and mitochondrial dysfunction, both of which lead to the suppression of orexin neurons. This inflammation can be localised in the hypothalamus. Inflammation directly leads to the suppression of orexin.
In some cases, low cortisol can also contribute to tiredness, but cortisol levels are controlled by your hypothalamus. Chronic inflammation generally increases cortisol levels.
Generally, there is no defect or problem with your adrenal glands themselves; They are not ‘fatigued’.
The fatigue true produce hormones that underlie the body’s mechanisms for coping with physical and mental stress. Overtraining in athletics, chronic anxiety, worry, nervous tension and other factors associated with excessive cortisol release are linked to adrenal exhaustion and fatigue. Over-reliance on caffeine and other stimulants also taxes the adrenals.
AdrenalMagic™ combines important nutrients and nutraceuticals that help reduce both oxidative stress and inflammation; Vitamin C, Rhodiola, Resveratrol, Bioflavonoids, Selenium, Zinc, ALA, B Vitamins, CoQ10 and pantothenic acid (B5).
AdrenalMagic™ works best when combined with a larger strategy which would include the following; Adequate Sleep, daily walks in open spaces, Sea salt , Potassium, Vit B1 (Nutritional Yeast), lowered sugar and fruit sugars (which depletes magnesium), massage / accupressure ; in particular the neck muscles, EFT, avoid coffee. Also hardy breakfast containing high fat and protein, avoiding grains and screens before bedtime, drinking Chamomile / Liquorice / Lemon Balm teas.
Most people today suffer from “adrenal exhaustion” stemming from the effects of poor nutrition and stress on the metabolism and immune system!
ARE YOU TIRED TODAY?
When a stressful lifestyle or other types of imbalances overwhelm the body, these glands become unhealthy and ineffective. This is the prime reason why most people are always saying they feel so TIRED! This condition may degenerate into Addison’s disease or total exhaustion and death. Early indications of adrenal gland exhaustion may include insomnia, extreme fatigue, arthritic joints or backs, low blood pressure, poor circulation, chills, dizziness or light headedness, waking up exhausted and with low levels of energy and extreme drowsiness in the afternoon. ‡
Recurrent increases in stress levels, both from psychological and physiological sources, can result in excess cortisol production, leading to a disrupted homeostasis and directly affecting the HPA axis, nervous system, and an array of other body systems. AdrenalMagic helps combat these effects by offering a blend of renowned herbal adaptogens and essential nutrients for complete stress support and adrenal renewal, as well as increased energy and endurance.*
Fatigue & Depression
Recently, a new concept of antidepressant mechanisms of action has been proposed based on the findings that antidepressants showed immediate antioxidant effects in the treatment of major depressive disorder (31). Increasing evidence from animal studies suggests that treatment with antioxidants can reduce oxidative stress and alleviate depressive-like behaviors
In addition to the stress-fighting compounds in key ingredients, such as Magnesium and Maca, AdrenalMagic contains Curcumin, Resveratrol & Liquorice , as high-concentration extracts. These ingredients have been clinically shown to ease short-term stress, promote normal levels of inflammation, promote a healthy outlook, support cognitive health, and increase physical endurance.*
Recognised for centuries by practitioners of Ayurvedic medicine for its potent adaptogenic qualities, ashwagandha promotes physical and mental health, and augments resistance against diverse environmental factors, revitalizing the body and supporting longevity.*
Rhodiola rosea has been studied for its performance-enhancing capabilities, as well as its therapeutic properties.* A variety of studies have shown that Rhodiola rosea supports nervous and cardiovascular health, promotes normal neurotransmitter and hypothalamicpituitary-adrenal axis function, as well as positive mood, optimal energy levels, and even longevity.* It also possesses an impressive safety profile, making it an attractive choice for managing the effects of stressors.* The Rhodiola rosea in AdrenalMagic contains the three active compounds which work synergistically to best promote endurance and increased energy levels, including rosavin (shown to help promote a healthy mood), rosin, and rosarin.
Resveratrol (trans-3,5,4′-trihydroxy-trans-stilbene, RES), a polyphenol component found mainly in grape and Polygonum cuspidatum (Japanese Knotweed), possesses multiple biological and pharmacological activities, including metabolism regulation and antioxidant effects. Results have demonstrated that RES alleviates depression-like behavior in a rat model of chronic unpredicted mild stress (CUMS) through its antioxidant effects and by ameliorating hyperactivity of the HPA axis. In addition, the monoaminergic system and the molecular markers related to depression were also altered by RES treatment . Several studies in recent years have implicated the Wnt signaling pathway in mood disorders such as bipolar disorder and major depression. Activation of the Wnt pathway leads to the inhibition of GSK-3ß, allowing ß-catenin to be stabilized in the cytosol and translocated to the nucleus, where it activates the transcription of target genes. (source)
In Indian Ayurvedic medicine, frankincense (Boswellia serrata) has been used for hundreds of years for treating arthritis. Extracts of Boswellia serrata have been clinically studied for osteoarthritis and joint function, particularly for osteoarthritis of the knee. Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn’s disease have been reported. A Boswellia extract marketed under the name Wokvel has undergone human efficacy, comparative, pharmacokinetic studies. Some see Boswellia serrata as a promising alternative to NSAIDs, warranting further investigation in pharmacological studies and clinical trials.
Known to support a healthy stress response and immunity, licorice (or Glycyrrhizin), has been specifically found in studies to lead to dose-dependent decreases in concentrations of cortisol, ACTH, aldosterone and K.* The herb contains a number of active compounds that support immunity and endocrine health. It also promotes the body s resistance to short term fatigue and helps maintain cortisol and DHEA levels within normal range.*
Pantethine is the active form of vitamin B5, It is essential in helping our body break down (metabolize) proteins, fats, and carbohydrates. Most importantly, pantethine is needed for our body to create adrenal steroids.
Curcuma Zedoaria, also known as white turmeric, is native to India and Indonesia. It is a very powerful, anti-inflammatory root that has been traditionally used to reduce common inflammatory issues like arthritis, swelling, pain and stiffness. It has been shown to stop the production of Tumor necrosis factor- alpha (TNF-a), a cytokine that is responsible for inflammation. Curcuma Zedoaria is very effective in reducing the swelling and inflammation of the prostate.
Vitamin C, Vitamin B, Zinc & ALA
Finally, vitamins C and pantethine play essential roles in adrenal health by participating in the synthesis and release of adrenal hormones.* Pantothenic acid is essential to the adrenal glands for production of the glucocorticoids through its formation of pantethine, a necessary precursor to coenzyme A and phosphopantethine, critical to numerous acylation reactions in the body (NIH.gov).
AdrenalMagic provides key ingredients, including Rhodiola rosea, and the highest-concentration Trans-resveratrol, to ease short-term stress, promote normal levels of inflammation, promote a healthy outlook, support cognitive health, and increase physical endurance.*
With traditional ingredients and cutting edge nutraceuticals backed by research, AdrenalMagic is an ideal solution for wide spectrum adrenal support.
Usage: Take 2 capsules twice per day or as directed by your qualified healthcare professional.
Contains:No fillers, No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
Quality Assurance Declaration
Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.
Nutraceutical DisclaimerThese statements have not been evaluated by the Food and Drug Administration or MHRA and the items are not intended to diagnose, treat, cure, or prevent any disease nor are they associated, endorsed, affiliated or sponsored by Anthony William, Medical Medium® Joe Tippens or Jim Gordon.