Adhesions form as a natural part of the body’s healing process after surgery in a similar way that a scar forms. The term “adhesion” is applied when the scar extends from within one tissue across to another, usually across a virtual space such as the peritoneal cavity. Adhesion formation post-surgery typically occurs when two injured surfaces are close to one another.
This often causes inflammation and causes fibrin deposits onto the damaged tissues. Taking anti-fibrotic herbs and enzymes (serrapeptase) which inhibit and slow down the adhesion process may provide valuable assistance for the immune system.
The fibrin then connects the two adjacent structures where damage of the tissues occurred. The fibrin acts like a glue to seal the injury and builds the fledgling adhesion, said at this point to be “fibrinous.”
Herbs that are reputed to aid healing of injuries, soften abdominal masses, and alleviate abdominal pain of various origins may act, in part, by breaking down undesirable collagens to alleviate the symptoms.
Antifibrotic and mass reducing herbs such as in AdhesioNIL™ are used to treat abdominal disorders such as uterine fibroids and liver fibrosis, and are also used to treat skin masses in scleroderma; it is possible that they function by increasing the degradation of fibrous tissue via hyaluronidase.
In body cavities such as the peritoneal, pericardial and synovial cavities, a family of fibrinolytic enzymes may act to limit the extent of the initial fibrinous adhesion, and may even dissolve it. In many cases however the production or activity of these enzymes are compromised because of injury, and the fibrinous adhesion persists.
If this is allowed to happen, tissue repair cells such as macrophages, fibroblasts, and blood vessel cells penetrate into the fibrinous adhesion and lay down collagen and other matrix substances to form a permanent fibrous adhesion.
In 2002, Giuseppe Martucciello’s research group showed a possible role could be played by microscopic foreign bodies (FB) accidentally contaminating the operative field during surgery. These data suggested that two different stimuli are necessary for adhesion formation: a direct lesion of the mesothelial layers and a solid substrate (FB). (source)
While some adhesions do not cause problems, others can prevent muscle and other tissues and organs from moving freely, sometimes causing organs to become twisted or pulled from their normal positions.
Herbs within AdhesioNIL™ (click on links for external studies and information)
- Bupleurum – hepaprotective and anti-fibrotic.
- Salvia miltiorrhiza (study) – anti-fibrotic, anti-metastatic.
- Scutellaria baicalensis (study) – dries dampness, hepaprotective, anti-fibrotic, inhibits intestinal motility, anti-tumors.
- Angelica sinensis – vitalises blood and promotes circulation, reduces abdominal pain, promotes secondary fibrinolysis.
- Fucoidan (from seaweed) – anti-fibrotic, reduces pain and inflammation (IL6)
- Turmeric – Anti-platelet, reduces blood pressure
- Red Peony – vitalise blood, disperses stagnant blood, controls pain accumulation in abdomen.
Individuals who are suffering from cancer can also have high levels of fibrin – which is dead protein cells that is created by cancer cells destroying nearby tissues.The body may collect these dead cells and isolate them in a particular area of the body. These masses are then known as benign tumours initially – which in turn can become cancerous. Additionally Tumor cells may take advantage of hyaluronidase, secreting it as a means of penetrating into the surrounding tissues and aiding metastasis. The enzyme is used pharmaceutically in administering certain drug therapies to help the drugs penetrate cells more easily.
Important Additional Dietary Suggestions
Serrapeptase inhibits the growth of fibrin-which may stop tumours from attaching to proteins and creating its own blood supply network. This is normally taken three times a day on an empty stomach. (source) Proteolytic enzymes are specific enzymes that metabolize protein. These enzymes are naturally produced by human body and other living organisms and help carry out essential functions. Supplements with these enzymes show a favorable anti-inflammatory effect on the tissues of the body.
Individuals who have recently had surgery and are in the healing phase should not use AdhesioNIL™ until their wounds have fully healed.
Quality Assurance Declaration
Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.
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