Folate is crucial for healthy growth and development, healthy homocysteine
metabolism, assisting DNA repair, and supporting neurological processes.
5MTHFACTIVE™ contains L-5-methyltetrahydrofolate (L-5-MTHF aka: 5MTHF), an active “methylated” form of folate, is included in this vegan suitable item.
It is best taken alongside B12BIACTIVE™ as they are co-factors in moderating homostysteine levels which can drive heart disease and inflammation.
Folate is a water-soluble B vitamin that occurs naturally in food, such as leafy green vegetables, citrus fruits, dried beans, and peas. L-5-methylfolate (5MTHF) requires no additional metabolic steps to be used by the body, thus it is often the preferred choice for those with absorption or metabolic defects who can’t properly convert the folate from leafy greens into the usable methylfolate.
L-5-MTHF efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function. L-5-MTHF is easily absorbed and used by cells. It is the predominant folate in circulation and the only folate that can cross the blood-brain barrier.*
Xenoestrogens or ‘Fake Estrogen’ is a modern Health epidemic, one of the things crucial in detoxifying xenoestrogens is a biochemical process in the body called Methylation.
Methylation is one of the most fundamental process’s in the body and about 40% of the global population has defects/mutations/polymorphism on a key gene (MTHFr) that is critical for the methylation process to occur.
Whats more is that it appears xenoestrogens can actually block the MTHF pathway which is supposed to help create the very detox agents (glutathione) which is essentially needed to get rid of the toxic substances. This can create a partial negative feedback loop.
Because the MTHFr genetic defect is so common, supplementing around/bypassing the defect with 5MTHF has almost miraculous panacea-like qualities in resolving a whole host of diseases and ailments. Methylation is the key to human life and optimal well being. It does the following:
- Turn on and off genes (Epigenetics – gene regulation)
- Process chemicals and toxins (biotransformation)
Build neurotransmitters (dopamine, serotonin, epinephrine)
- Process hormones (estrogen)
- Build immune cells (T cells, NK cells)
- DNA and RNA synthesis (Thymine aka 5-methyluracil)
- Produce energy (CoQ10, carnitine, ATP)
- Produce protective coating on nerves (myelination)
When methylation does not function properly, it is now known to be of the primary root causes of the following conditions:
Autism, Cancer, Fibromyalgia, Chronic Fatigue Syndrome, Diabetes, Pulmonary Embolisms, Cleft Palette, Spina Bifida, Parkinson’s, Neural Tube Defects, Atherosclerosis, Immune Deficiency, ADD/ADHD, Multiple Sclerosis, Alzheimer’s, Dementia, Chemical Sensitivity, Congenital Heart Defects, Depression, Alcoholism, Addictive Behaviors, Insomnia, Down’s Syndrome, Chronic Viral Infection, Thyroid Dysfunction, Neuropathy, Recurrent Miscarriages, Infertility, Anxiety, Schizophrenia, Bipolar, Allergies.
The MTHFR gene mutation is also believed to be caused by Pyluria (HPU or KPU) which is a leeching away of key minerals such as Zinc, Biotin, Vitamin B6 and Manganese in the urine due to a number of enzyme pathways being blocked which also lower Glutathione. This mutation may be tested using urine analysis. see the HPU / KPU symptoms here. We are soon to have a supplement available for supporting this condition.
The optimal dosage of MethylFolate can vary per individual and even vary within the individual. The aim is to take enough to start to sense an effect such as the start of anxiety or a headache after 5 mins, which is the ideal level. Be sure to ramp up 5MTFH slowly over a few days starting with 1 drop but only after you have established good tolenace for B12BIACTIVE and have B complex vitamins in your diet. If you do take too much and don’t feel so well, take Vitamin B3 as Nicotinamide (aka Niacinamide) at 50mg every hour until you feel normal. Read more on Side Effects Here Very important supplement for women who are prgenant but also support with Calcium Folinate and a good multivitamin.
Quality Assurance Declaration
Werone.co endeavors to use the most potent source materials within our formulas. Our herbal extracts are sourced and tested by the only Government-certified large scale producer of crude herb (powder-free) TCM concentrates in Asia who manufacture to GMP / ISO 9001/2000 pharmaceutical grade and also operate an ISO17025/TAF-certified laboratory where they subject all plant extracts to strict quality inspections free from heavy metals, pesticides or microbes before release to the clinics all over the world. The formulas and tinctures are assembled without fillers in small batches by a BHMA member herbal dispensary.
Nutraceutical DisclaimerThese statements have not been evaluated by the Food and Drug Administration or MHRA and the items are not intended to diagnose, treat, cure, or prevent any disease nor are they associated, endorsed, affiliated or sponsored by Anthony William, Medical Medium® Joe Tippens, Jane McLelland or Jim Gordon.