5MTHFACTIVE™ – Methylfolate Drops
$21.43
- GBP: £16.50
- EUR: €18.56
- AUD: $29.97
Earn 214 points upon purchasing this product.
Folate is crucial for healthy growth and development, healthy homocysteine
metabolism, assisting DNA repair, and supporting neurological processes.
5MTHFACTIVE™ contains L-5-methyltetrahydrofolate (L-5-MTHF aka: 5MTHF), an active “methylated” form of folate, is included in this vegan suitable item.
Description

Folate is crucial for healthy growth and development, healthy homocysteine
metabolism, assisting DNA repair, and supporting neurological processes.
5MTHFACTIVE™ contains L-5-methyltetrahydrofolate (L-5-MTHF aka: 5MTHF), an active “methylated” form of folate, is included in this vegan suitable item.
It is best taken alongside B12BIACTIVE™ as they are co-factors in moderating homostysteine levels which can drive heart disease and inflammation.
Folate is a water-soluble B vitamin that occurs naturally in food, such as leafy green vegetables, citrus fruits, dried beans, and peas. L-5-methylfolate (5MTHF) requires no additional metabolic steps to be used by the body, thus it is often the preferred choice for those with absorption or metabolic defects who can’t properly convert the folate from leafy greens into the usable methylfolate.
L-5-MTHF efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function. L-5-MTHF is easily absorbed and used by cells. It is the predominant folate in circulation and the only folate that can cross the blood-brain barrier.*
Xenoestrogens or ‘Fake Estrogen’ is a modern Health epidemic, one of the things crucial in detoxifying xenoestrogens is a biochemical process in the body called Methylation.
Methylation is one of the most fundamental process’s in the body and about 40% of the global population has defects/mutations/polymorphism on a key gene (MTHFr) that is critical for the methylation process to occur.
Whats more is that it appears xenoestrogens can actually block the MTHF pathway which is supposed to help create the very detox agents (glutathione) which is essentially needed to get rid of the toxic substances. This can create a partial negative feedback loop.
Because the MTHFr genetic defect is so common, supplementing around/bypassing the defect with 5MTHF has almost miraculous panacea-like qualities in resolving a whole host of diseases and ailments. Methylation is the key to human life and optimal well being. It does the following:
- Turn on and off genes (Epigenetics – gene regulation)
- Process chemicals and toxins (biotransformation)
Build neurotransmitters (dopamine, serotonin, epinephrine) - Process hormones (estrogen)
- Build immune cells (T cells, NK cells)
- DNA and RNA synthesis (Thymine aka 5-methyluracil)
- Produce energy (CoQ10, carnitine, ATP)
- Produce protective coating on nerves (myelination)
When methylation does not function properly, it is now known to be of the primary root causes of the following conditions:
Autism, Cancer, Fibromyalgia, Chronic Fatigue Syndrome, Diabetes, Pulmonary Embolisms, Cleft Palette, Spina Bifida, Parkinson’s, Neural Tube Defects, Atherosclerosis, Immune Deficiency, ADD/ADHD, Multiple Sclerosis, Alzheimer’s, Dementia, Chemical Sensitivity, Congenital Heart Defects, Depression, Alcoholism, Addictive Behaviors, Insomnia, Down’s Syndrome, Chronic Viral Infection, Thyroid Dysfunction, Neuropathy, Recurrent Miscarriages, Infertility, Anxiety, Schizophrenia, Bipolar, Allergies.
The MTHFR gene mutation is also believed to be caused by Pyluria (HPU or KPU) which is a leeching away of key minerals such as Zinc, Biotin, Vitamin B6 and Manganese in the urine due to a number of enzyme pathways being blocked which also lower Glutathione. This mutation may be tested using urine analysis. see the HPU / KPU symptoms here. We are soon to have a supplement available for supporting this condition.
Suggested Usage
The optimal dosage of MethylFolate can vary per individual and even vary within the individual. The aim is to take enough to start to sense an effect such as the start of anxiety or a headache after 5 mins, which is the ideal level. Be sure to ramp up 5MTFH slowly over a few days starting with 1 drop but only after you have established good tolenace for B12BIACTIVE and have B complex vitamins in your diet. If you do take too much and don’t feel so well, take Vitamin B3 as Nicotinamide (aka Niacinamide) at 50mg every hour until you feel normal. Read more on Side Effects Here Very important supplement for women who are prgenant but also support with Calcium Folinate and a good multivitamin.
Nutraceutical DisclaimerThese statements have not been evaluated by the Food and Drug Administration or MHRA and the items are not intended to diagnose, treat, cure, or prevent any disease nor are they associated, endorsed, affiliated or sponsored by Anthony William or Medical Medium®. |
Additional information
Weight | 85 g |
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Returns and Exchanges
You can return unwanted items by post within 7 working days of receipt of your goods.
- You have 14 calendar days to return an item from the date you received it.
- Only items that have been purchased directly from Us.
- Please ensure that the item you are returning is unopened and in re-saleable condition.
- Email us for a return address and procedure.
Donation/Gifting placed before 12pm will usually be shipped the sameday, if there is any stock issue we will contact you to discuss. The main shipping choices available during the final stage of our gifting cart are: 2 to 3 Day - Monday to Friday, 'may' deliver to residential addresses on a Saturday. Next Day - Monday to Friday, 'may' deliver to residential addresses on a Saturday. Takes from 5 to 10 Days - Monday to Friday, 'may' deliver to residential addresses on a Saturday. 5 to 7 days - Monday to Friday, 'may' deliver to residential addresses on a Saturday. 1 to 2 days - Monday to Friday, Only available to: Belgium, France, Germany, Greece, Ireland, Italy, Netherlands, Portugal, Spain, Sweden. from £9.00 or 3 day courier service from £21. USA shipments will only be sent by post due to customs issues with courier services. England, Scotland, Norther Ireland, Wales, Channel Islands, I.O.M Irish Republic, Belgium, France, Germany, Greece, Hungary, Italy, Netherlands, Portugal, Romania, Spain , Med. Islands , Austria, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, Hungary, Israel, Luxembourg, Lithuania, Latvia, Malta, Norway, Poland, Russia, Romania, Slovakia, Slovenia, Serbia, Sweden, Africa , Albania, Algeria, Australia, Botswana, Bahamas, Canada, Canary Islands, Croatia, Egypt, Jamaica, Jordan, Kenya, Malaysia, Mauritius, Monaco, Moldova, Morocco, Norway, South Africa, Sudan, Switzerland, Syria, Turkey, Ukraine, Zambia, Argentina, Barbados, Brazil, Chile, Colombia, Costa Rica, Equador, Israel, Jamaica, Kuwait, Libya, Lebanon, Mexico, Oman, Peru, Puerta Rica, Saudi Arabia, Singapore, Taiwan, Thailand, UAE, USA(surface post only) Uraguay, Yemen, Australia, Bali, China, Hong Kong, Indonesia, Japan, South Korea, Malaysia, New Zealand. British Isles / Royal Mail >0.5kg 1kg 2kg 5kg Europe + Scandinavia + Surface Mail (approx 7 -10 days) - NOT-TRACKED >2kg 3kg >0.25kg 0.5-1kg 1-2kg 2-3kg >250g >500g >750g 1kg £21.00 Use Cour. We can provide a refund if you are unhappy with your gift but you will need to pay the return costs and the individual items must not have been opened and must be returned in original condition and with all packaging intact. Any refunds which are authorised should be returned to the address on the paperwork with a copy of it along with your reason for return. Items MUST be returned UNOPENED and in the condition they were sold in. Must be received before 11.00am to be despatched on the same day (note: £1 is approx $1.30 USD & €1.14 EUR, use this Currency Convertor to find the latest exchange rates, or select the currency flag in the top right corner of the webpage) Delivery - British Isles Shipping (BI):
British Isles Delivery - FREE if over £35 order value - [£0.00] 2nd Class Royal Mail - NOT-TRACKED
British Isles Delivery - Royal Mail up to 2Kg - [£3.50 to £6.00]
Europe / Scandinavia- Surface Mail up to 2Kg - [£4.56 to £15.00] or FREE if order value over £77.00 (€85) - NOT-TRACKED
Europe / Scandinavia- Surface Mail up to 3Kg - TRACKED! - [£7.85 - £16.50]
UPS EXPRESS (1 - 2 days) Some of Europe - Courier up to 2Kg to 3kg - [£34.00 to £38.00]
Outside Europe / International - [7-10 days] - Mail and/or Courier(Except USA),
* Please ensure that someone is available to sign for the parcel at the delivery address. You may provide a work address if you wish during the checkout process. In UK Royal Mail will only make ONE delivery attempt, if nobody is available at the address, they will leave a card and expect you to contact them, they cannot leave with a neighbour unless you pre-arrange this with us. A re-delivery will cost £3.00 and a change of address will be £6.50, you may also collect from their collection office. If the shipment is not collected after 4 days they will return it back to us, re-deliveries will be chargeable.
Please Note: These costs are for most items. We reserve the right to adjust costs to reflect the additional cost of shipping items of greater than average weight . Shipping & Handling is based on weight of the Order using the following schedule (all donations are in GBP and not subject to VAT) Delivery Zones Worldwide
Note, if you choose the wrong delivery zone, we will re-calculate the delivery charge and advise you by email if there is any donation shortfall to ask you to pay the balance on paypal.. British Isles / Free if not urgent! Surface Mail / Courier from £10
Europe / Scandinavia - Surface Mail
Outside Europe / Asia / USA / Southern Hemisphere - Surface Mail or Courier
Delivery Region (Regular Mail and Couriers)
Delivery Costs (Approx.)
British Isles - FREE if over £35 order value
(5 to 7 days)>5kg FREE but Not Insured!
(2 - 3 days)
£3.50
£4.00
£6.00
£15.00
>0.25kg
£4.35 750g £6.50
>1kg
£8.502kg
£12.50
Europe UPS EXPRESS (approx 1 - 2 days)
£34.00
£38.00
Europe + Scandinavia + Surface Mail (approx 7 -10 days) - TRACKED
£7.85
£15.00
£16.90
Use Cour.
Outside EU (approx 7 - 10 days)
(7-10 days mail
£5.00
£9.00
£12.00
Outside EU Courier (Except USA)
(3 days UPS, option is insured) >250g
£24.00>500g
£24.00>750g
£26.001kg
£26.00Warranty and Returns Policy
USA and International Gifts:
Special Delivery are a fast and reliable service. The delivery to the British Isles is a 1-2 day service (subject to stock) when choosing these methods. We cannot 'guarantee' a nextday delivery, though often it will arrive nextday (except during Holiday Periods). Please make your choice on the checkout page of our gifting cart. Parcels weighing over 1kg in weight will automatically be sent using Courier nextday from day of despatch unless otherwise specified. Most orders placed before 12 Noon are usually be despatched sameday but we cannot guarantee this, [email us] to find out what stage of your gift is at. Donation/Gifts placed late Friday afternoon or on a weekend, will not be sent until the following Monday or Tuesday. Should you wish to have a Saturday Delivery, there is an additional cost of £18.