Metabolic Fuel Inhibition Strategy - MFIS

The aim of MFIS is to block all fuels and target the key dis-regulated genes to lower the energy available so that mutant cells commit suicide & homeostasis is established.

Resources: Protocols for various tumor types may be found within our BiohackIT™ phone Web App :  Sign-up Here

Cancer metabolic reprogramming has been recognised as one of the ten cancer hallmarks by Drs. Hanahan and Weinberg in their seminal review paper published in 2011.

Metabolic Fuel Inhibition is a Strategy based upon this information.

Hallmarks of Cancer: The Next Generation – 2011

Cancer Metabolic Reprogramming – 2014

Autophagy and Cancer Metabolism – 2014


Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies – 2014

A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in the development and progression of diverse tumors – 2016